Journal:

Article Title: Deep Tissue Microscopic Imaging of the Kidney with a Gradient-Index Lens System

doi: 10.1016/j.optcom.2007.08.074

Figure Lengend Snippet: Gradient-index lenses. A, GRIN lens with one pitch length and examples of image transfer through a GRIN lens. Images at the entrance surface of a ½-pitch lens are inverted at the exit surface. Images transfer through an one pitch long GRIN lens maintain their orientations with a magnification factor of one; B, GRIN lens with a pitch length slightly shorter than ¼-pitch; C, Refractive index profile of a GRIN lens

Article Snippet: GRIN lens probe is used in conjunction with a Carl Zeiss LSM 510 two-photon microscope system.

Techniques: Refractive Index

Journal:

Article Title: Deep Tissue Microscopic Imaging of the Kidney with a Gradient-Index Lens System

doi: 10.1016/j.optcom.2007.08.074

Figure Lengend Snippet: Schematics of the imaging system. GRIN lens probe is used in conjunction with a Carl Zeiss LSM 510 two-photon microscope system. The triplet GRIN lens microendoscopic probe is attached to a 20X air objective through a 5-axis optical fiber translator. The Z-control motor moves the sample stage which carries the kidney tissue samples or live animals for microendoscopic imaging.

Article Snippet: GRIN lens probe is used in conjunction with a Carl Zeiss LSM 510 two-photon microscope system.

Techniques: Imaging, Microscopy, Control

Journal:

Article Title: Deep Tissue Microscopic Imaging of the Kidney with a Gradient-Index Lens System

doi: 10.1016/j.optcom.2007.08.074

Figure Lengend Snippet: Fluorescence image of a renal tubule labeled with Prodan acquired using the GRIN lens imaging system. Zoom factor was set to 6. Depth of imaging: ~3 mm; Excitation: 800 nm; Field of view: a 70 μm diameter circle. Scale bar: 10 μm.

Article Snippet: GRIN lens probe is used in conjunction with a Carl Zeiss LSM 510 two-photon microscope system.

Techniques: Fluorescence, Labeling, Imaging

Journal:

Article Title: Deep Tissue Microscopic Imaging of the Kidney with a Gradient-Index Lens System

doi: 10.1016/j.optcom.2007.08.074

Figure Lengend Snippet: A Z-series fluorescence image of the kidney stained with Prodan acquired using the GRIN lens imaging system. Z-stack dimension: 610 μm; Depth of imaging: 2.5–3.1 mm beneath the cortex surface; Excitation: 800 nm.

Article Snippet: GRIN lens probe is used in conjunction with a Carl Zeiss LSM 510 two-photon microscope system.

Techniques: Fluorescence, Staining, Imaging

Journal:

Article Title: Deep Tissue Microscopic Imaging of the Kidney with a Gradient-Index Lens System

doi: 10.1016/j.optcom.2007.08.074

Figure Lengend Snippet: Montage of images at different depth acquired while the GRIN lens probe was moving deeper into the kidney tissue. A portion of a renal tubule and other structural features was visualized at depth from 2.59 mm to 2.94 mm beneath the kidney surface. Scale bar: 10 μm

Article Snippet: GRIN lens probe is used in conjunction with a Carl Zeiss LSM 510 two-photon microscope system.

Techniques:

Journal:

Article Title: Deep Tissue Microscopic Imaging of the Kidney with a Gradient-Index Lens System

doi: 10.1016/j.optcom.2007.08.074

Figure Lengend Snippet: Microendoscopic images of live kidney stained with nuclear dye. Distance between adjacent images is 50 μm. From A to D the GRIN lens probe moved 150 μm into the kidney tissue and these images recorded the relative movement of the cells passing through the GRIN lens probe. Scale bar: 10 μm

Article Snippet: GRIN lens probe is used in conjunction with a Carl Zeiss LSM 510 two-photon microscope system.

Techniques: Staining

Journal:

Article Title: Deep Tissue Microscopic Imaging of the Kidney with a Gradient-Index Lens System

doi: 10.1016/j.optcom.2007.08.074

Figure Lengend Snippet: Schematics of the imaging system. GRIN lens probe is used in conjunction with a Carl Zeiss LSM 510 two-photon microscope system. The triplet GRIN lens microendoscopic probe is attached to a 20X air objective through a 5-axis optical fiber translator. The Z-control motor moves the sample stage which carries the kidney tissue samples or live animals for microendoscopic imaging.

Article Snippet: It should be noted that the 610-μm continuous traveling distance of the GRIN lens microendoscopic probe is the limit of the current Zeiss microscope operating system set for automated Z-stack image data acquisition.

Techniques: Imaging, Microscopy, Control

Journal:

Article Title: Deep Tissue Microscopic Imaging of the Kidney with a Gradient-Index Lens System

doi: 10.1016/j.optcom.2007.08.074

Figure Lengend Snippet: Microendoscopic images of live kidney stained with nuclear dye. Distance between adjacent images is 50 μm. From A to D the GRIN lens probe moved 150 μm into the kidney tissue and these images recorded the relative movement of the cells passing through the GRIN lens probe. Scale bar: 10 μm

Article Snippet: It should be noted that the 610-μm continuous traveling distance of the GRIN lens microendoscopic probe is the limit of the current Zeiss microscope operating system set for automated Z-stack image data acquisition.

Techniques: Staining